Neuregulin-1: A Potential Endogenous Protector in Perinatal Brain White Matter Damage
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چکیده
منابع مشابه
Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage.
Brain white matter damage, an important antecedent of long-term disabilities among preterm infants, has both endogenous and exogenous components. One of the endogenous components is the paucity of developmentally regulated protectors. Here we expand on this component, discussing the potential roles of one putative protector, neuregulin (NRG)-1, in brain development and damage. We outline how NR...
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Perinatal brain damage in the mature fetus is usually brought about by severe intrauterine asphyxia following an acute reduction of the uterine or umbilical circulation. The areas most heavily affected are the parasagittal region of the cerebral cortex and the basal ganglia. The fetus reacts to a severe lack of oxygen with activation of the sympathetic-adrenergic nervous system and a redistribu...
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ژورنال
عنوان ژورنال: Neonatology
سال: 2007
ISSN: 1661-7800,1661-7819
DOI: 10.1159/000111119